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In Vitro Fertilization Treatments

To bring a child into the world, and thereby be credited as the father and mother is definitely much more than just a job.

Every couple faced with infertility has to take a tough decision of choosing the right place for IVF treatments. The answer to the question Why choose us lies in the fact that, with our partner`s experience and knowledge, under current circumstances, we will offer you the best IVF treatments and the highest chance for success for affordable IVF treatment cost.

Discover our services below.

One Stop Fertility Clinic

How the procedure is performed?

One-day diagnosis means that the couple visits us on a certain day of the cycle with predetermined laboratory results which must be determined on an exact corresponding day of the cycle. This is followed by an interview with a doctor, a complete gynecological and ultrasound examination, and then by going to the operational theatre (although the procedure can be performed in an outpatient clinic) where, most often in short-term intravenous anesthesia (the procedure may be done when the patient is awake), a camera enters the uterus, and then slips through a small puncture, a couple of millimeters in diameter at the bottom of the vagina, into the abdominal cavity.

In this way, we can directly visualize the inside of the uterus, fallopian tubes and ovaries. The contrast passes through fallopian tubes, which is then measured (“blowing”). Certain detected problems can be surgically treated within the same procedure. The procedure itself takes 15-20 minutes for the most part, and while the woman is being examined, reproductive biologists are checking the semen analysis of the man who brings a fresh sperm specimen from home or produces one on site.

How much does it last?

After a break of 1-2 hours after the end of the procedure, patients receive a full set of results from the doctor, with documented photographs of the findings, before and after the surgery, a complete picture of the situation is made upon which the best plan selected for further treatment.

Laparoscopy

Laparoscopy, also known as diagnostic laparoscopy, is a surgical diagnostic procedure used to examine the organs inside the abdomen. It’s a low-risk, minimally invasive procedure that requires only small incisions.

When is laparoscopy used?

Laparoscopic gynecology is most commonly used in the following conditions:

  • Checking the passage of the fallopian tubes, with an operative procedure on the fallopian tubes, if for any reason they are damaged.
  • Operative removal of tuberculosis (salpingectomy) in non-pregnant pregnancy and all other conditions where a particular process damages tuberculosis to the extent and where their leave offers more harm than benefit.
  • All types of benign ovarian tumors (primarily cystic ovaries).
  • All forms and all stages of the weight of endometriosis.
  • Myoma uterus, both subserotic and intramural (on the outside and in the uterine wall).
  • Removing the uterus for a number of reasons (benign and malignant).
  • The number of conditions in the field of urogynecology (urinary disorders), and other varied gynecological pathologies.

IUI – Intrauterine insemination

Intrauterine insemination is a method of medically assisted reproduction, which does not involve In vitro fertilization, but helps a couple in spontaneous achieving of pregnancy. The procedure is simple, safe and often successful in helping the infertile couple. We believe that this method, as well as all other methods of  infertility treatment, may be carried out only after the complete diagnosis of the infertile couple, in order to avoid certain complications, and only when a doctor’s opinion is that the chances of success of this method are satisfactory.

Who should consider IUI treatment?

Insemination is indicated primarily in patients with infertility of unknown origin, but also in patients with a mild form of male infertility, ovulatory problems, lack of spontaneous ovulation, in cases where there is presence of antibodies to the sperm, problems at the level of the cervix, and numerous other conditions. This procedure can be performed in a spontaneous cycle or in a cycle with certain slight stimulation of ovulation in women, which we usually prefer as it gives a greater chance for success.

How the procedure is performed?

The procedure is performed after the appropriate preparatory studies, when therapy to stimulate ovulation is determined. Development of follicles is monitored by ultrasound and hormonally, and then, in a certain stage, ovulation is triggered. The act of insemination is performed at this stage, which can be compared with regular gynecological examination by the inconvenience. Under the speculum, through the cervical canal, sperm solution, which is previously prepared and processed by reproductive biologists, is injected in order to select the best sperm in the most appropriate conditions, in order to facilitate an opportunity for the realization of pregnancy. Upon completion of the procedure, patients are advised not hibernation, but on the contrary, continued effort on spontaneous pregnancy. In the stimulated cycle, a success of the procedure, according to the relevant professional literature, is 10-15% per cycle. It is mainly advised performance of 3-6 cycles of insemination. To selected couples, this gives greater overall opportunity for the realization of the pregnancy in this way, than if they had undergone one cycle of in vitro fertilization. However, if the pregnancy is not happening in this way, we believe that the couple should be promptly suggested of the possibility of in vitro fertilization.

ICSI – Intra-cytoplasmic Sperm Injection

ICSI – intracytoplasmic sperm injection, is the technique of fertilization of the egg cell from the group of micro-manipulation techniques, where a single spermatozoid is injected directly into the cytoplasm of the egg cell, and thus achieves its fertilization and an embryo creation. This method was developed in 1991 and has brought a revolution in the treatment of severe forms of male infertility, which until then had very little chance of success by applying the classical IVF procedure. It is sufficient to have available a very low quantity of sperm using ICSI procedure. Certain IVF clinics switched to ICSI as a standard procedure in all situations, due to work standardization and less chance of fertilization failure. However, even this may not be the best solution because the sperm selection is done mainly on the basis of morphological assessment by embryologists. This procedure does not apply to natural selection of the best spermatozoid.The selection of the best spermatozoid (PICSI, MACS).

When is ICSI method usually used?

ICSI is used by default in following situations:
• More severe forms of pathological spermogram (reduced number, motility and proportion of normal spermatozoids)
• After all the techniques of surgical spermatozoid extraction (TESA, TESE)
• For normal spermogram when in previous cycles has been a low rate of fertilization of egg cells or even the complete absence of fertilization
• In case of large number of egg cells available, even in cases of normal spermogram, it is advisable to use fertilization of one part by IVF method and the other part using the ICSI method, to avoid the chance of fertilization failure.

Guaranteed IVF program

About the Program

Guaranteed IVF program with own oocytes offers multiple IVF cycles for a fixed price, significant savings and a 30% refund in case pregnancy is not achieved.

Includes up to 3 patient`s egg collections under general anesthesia and unlimited frozen embryo transfers (if there are surplus embryos obtained after fresh IVF cycles) in between each fresh cycle until pregnancy is confirmed or all embryos are used.

Guaranteed IVF program will help to overcome different obstacles and offer much higher chances for successful outcome with patient’s own oocytes.

Money Back System.

If no pregnancy is achieved (pregnancy is determined by the ultrasound examination which will confirm baby`s heartbeat on 6th week of pregnancy), 30% of the program total cost will be refunded.

*The program is valid for the period of 16 months from the moment of signing the pre-agreement.

Cumulative success pregnancy rate with Guaranteed IVF:

  • 1st embryo transfer – 64%
  • 2nd embryo transfer – 86%
  • 3rd embryo transfer – 97 %
  • 4th embryo transfer – 100 %

TESE

Testicular sperm aspiration procedure (TESA) is a procedure performed for men with obstructive azoospermia (zero sperm count due to an obstruction) who are having sperm retrieved for In Vitro Fertilization/ Intracytoplasmic sperm injection (IVF/ICSI).

In some individuals, spermatozoa may not be present in the ejaculate. This condition is called Azoospermia. This can be either due to problems in sperm production itself or due to obstruction to the flow of semen during ejaculation. Congenital anomalies may be relatively uncommon in the general population, but can occur in up to 2 percent of infertile men. The newest of the aspiration techniques is testicular sperm retrieval (TESA – TESE).

CET Cryo-embryo transfer

Cryopreservation methodology enables the preservation of embryos in a frozen state for their later use in IVF treatments. During cryo-embryo transfer the embryos are thawed, their quality is assessed and after a brief period of cultivation, they are inserted into the uterine cavity using a thin transfer catheter.

PGD and PGS

Preimplantation genetic diagnosis (PGD) and Preimplantation genetic screening (PGS)

Preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) are the most advanced and revolutionary methods of treating infertility by using highly specialized molecular genetic techniques in examining the state of the embryo.

What is PGD and when to use it?

Preimplantation genetic diagnosis (PGD) is a sophisticated and delicate procedure, where the laser is used to take out an embryonic cell, which is obtained through In vitro fertilization. This procedure does not interfere with the further course of development of the embryo. Obtained cell embryo is then sent to a genetic laboratory, where it is analyzed for the presence of particular genetic diseases by the most advanced molecular techniques. In this way, in certain situations, when there is a risk of transmission of inherited diseases to offspring, it is possible to be diagnosed whether an embryo has the gene for a particular disease. Only healthy embryos are then returned to the uterus, preventing the occurrence of disease in the child. Indications for the above procedure may be various, and relate primarily to rare monogenic diseases that are known to exist in the family, with parents, siblings and other relatives.

What is PGS and when to use it?

Preimplantation genetic screening (PGS) is a procedure that technically does not differ from PGD procedure, except that aims to analyze the total number of chromosomes of embryos that during the procedure of IVF treatment should be returned to the womb. In fact, it was said that the reason for the greatest number of unsuccessful cycles (over 80%) lies in the fact that the embryo, which was returned to the womb, even though it had a great look, it was aneuploid (or did not have a normal number of chromosomes). These conditions are very common, especially with the older age of the mother, and most often are associated with implantation failure or miscarriage. Only in rare cases, these embryos can survive pregnancy (such as embryos with Down syndrome). In certain situations, when the woman is over 37, or when there were previous unsuccessful attempts, or if it is a wish of parents, all embryos could be tested using the above technique, to determine whether they have the normal number of chromosomes, in order to return to the womb only chromosomal correct embryos.

Cryopreservation

Cryopreservation is a set of revolutionary technologies in the field of cryobiology by which cells and tissues can be successfully frozen at extremely low temperatures that allow virtually stopping of biological process of aging and cell death, and more importantly, then, after a period of several years to several decades, successfully could be unfrozen while retaining its full functionality. Decades of scientific discoveries, and development of specific freezing substances that help cells to survive this process, so-called cryoprotectants, as well as specific freezing mechanisms on the basis of slow freezing method used earlier, and vitrification method used nowadays, have contributed a successful freezing and later unfreezing with huge survival rate of almost all human cells, including those most vulnerable – egg.

What is a success rate?

The survival rate of egg cells by advanced methods of vitrification has reached a staggering 95% or more nowadays, even though a few years ago were only 20%. The fact that almost 40% of children who were born after In vitro fertilization procedures their way began as an embryo which was frozen at fertilization, and subsequently unfrozen by cryopreservation methods, speaks in favor of safety of the procedure. That demonstrates the efficiency and safety of the Procedure, since in these situations is recorded even a lower rate of complications in pregnancy. Today, cryopreservation is successfully applied to almost all types of human cells, byroutinely freezing of sperm, egg cells, embryos, and the tissue around the testicles and ovaries in certain indications.

Hysteroscopy

A hysteroscopy is a way for your doctor to look at the lining of your uterus. The hysteroscope has a light and camera hooked to it so your doctor can see the lining on a video screen. It also may be done to see if a problem in your uterus is preventing you from becoming pregnant.

Hysteroscopy is used as the only and primary for the operative treatment of the following conditions (some of which are not visible on ultrasound before it, and only seen on hysteroscopy):

  • Stenosis and another problem of the cervical canal
  • Polipi the body of the womb
  • Presence of intrauterine Adults Asherman’s syndrome
  • Submucosal myomas
  • Presence of septum in septum in the uterus, as well as in the evaluation of all uterine abnormalities
  • Numerous conditions that fall into the “invisible” pathology of the uterus by other methods, inflammatory conditions of the uterus, fibrotic barriers and many others.

Laparoscopy

Laparoscopy, also known as diagnostic laparoscopy, is a surgical diagnostic procedure used to examine the organs inside the abdomen. It’s a low-risk, minimally invasive procedure that requires only small incisions.

Laparoscopic gynecology is most commonly used in the following conditions:

  • Checking the passage of the fallopian tubes, with an operative procedure on the fallopian tubes, if for any reason they are damaged.
  • Operative removal of tuberculosis (salpingectomy) in non-pregnant pregnancy and all other conditions where a particular process damages tuberculosis to the extent and where their leave offers more harm than benefit.
  • All types of benign ovarian tumors (primarily cystic ovaries).
  • All forms and all stages of the weight of endometriosis.
  • Myoma uterus, both subserotic and intramural (on the outside and in the uterine wall).
  • Removing the uterus for a number of reasons (benign and malignant).
  • The number of conditions in the field of urogynecology (urinary disorders), and other varied gynecological pathologies.

Laparotomy

A laparotomy is a surgical incision into the abdominal cavity. It is performed to examine the abdominal organs and aid diagnosis of any problems.

The surgical incision for the opening of the anterior abdominal wall and access to the organs of the small pelvis can be a longitudinal or transverse cut, and the decision depends on the type of illness and the required extent of the surgical procedure, the size of the organ or the change that should be surgically removed, the age of the patient and her general health and condition as well as any previous operations.

Budget Egg Donation Program

About the Program

We are extremely excited to inform you about our new Budget Egg Donation Program with vitrified donor oocytes for just 2950 €. 

You have the perfect chance to choose immediately available oocytes from our own extended Egg Donor Bank that includes over 5.000 oocytes from the wide range of donors and start the treatment program for an exclusive price!

You will be provided with the access to the Egg Donor Catalog and all necessary information to start your journey to parenthood.

Includes:

  • Initial consultation with fertility specialist (personal doctor and medical coordinator who will be in constant contact with you at all stages of your treatment).
  • Free 7-days access to broad Egg donor catalog with more than 5.000 oocytes from donors with different characteristics.
  • Vitrified oocyte donor selection process (1 set – 12 oocytes).
  • Personalized treatment plan for each patient.
  • Endometrial lining stimulation protocol.
  • Warming of vitrified oocytes.
  • Egg donor compensation.
  • The semen analysis and sperm preparation (it can be partner’s or donor’s sperm).
  • Intracytoplasmic sperm injection (ICSI) of thawed oocytes with partner’s or donor’s sperm.
  • Embryo cultivation.
  • Embryo transfer.
  • Detailed embryological development report and photo of transferred embryos.
  • Assistance with visa applications, hotel and travel arrangements.
  • 2 Airport Transfers and the complimentary city tour with a guide.
  • Patient support during and after the treatment program.

IVF with fresh donor oocytes

IVF treatment with fresh donor oocytes includes:

  • Initial consultation with fertility specialist (personal doctor and medical coordinator who will be in constant contact with you at all stages of treatment).
  • 3-days free access to broad Egg donor catalog with more than 450 completely screened egg donors with different phenotypes .
  • Free Egg donor selection process (with personal assistance from your doctor).
  • Personalized treatment planning for each patient.
  • Endometrial lining stimulation protocol.
  • Egg donor medical and psychological screening, medication, stimulation.
  • Donor egg retrieval with anesthesia.
  • Egg donor compensation.
  • The semen analysis and sperm preparation.
  • Intracytoplasmic sperm injection (ICSI).
  • Embryo culture.
  • Embryo transfer .
  • Detailed embryological development report and photo of transferred embryos.

IVF with vitrified donor eggs

IVF treatments with vitrified donor eggs includes:

    • Initial consultation with fertility specialist (personal doctor and medical coordinator who will be in constant contact with you at all stages of  treatment).
    • Free 3-days free access to broad Egg donor catalog with more than 450 completely screened egg donors with different phenotypes.
    • Vitrified oocyte donor selection process (1 set – 6-8 oocytes).
    • Personalised treatment planning for each patient.
    • Endometrial lining stimulation protocol.
    • Warming of vitrified oocytes.
    • Egg donor compensation.
    • The semen analysis and sperm preparation (it can be partner`s or donor`s sperm).
    • Intracytoplasmic sperm injection (ICSI) of thawed oocytes with partner`s or donor`s sperm.
    • Embryo culture.
    • Embryo transfer.
  • Detailed embryological development report and photo of transferred embryos.

Combined IVF with own and donor oocytes

Combined IVF treatment with own and donor oocytes includes:

    • Initial consultation with fertility specialist.
    • Personalised treatment planning for each patient.
    • Ultaround monitoring of ovarian stimulation.
    • Hormonal monitoring of ovarian activity.
    • Pretransfer lining preparation.
    • Warming of vitrified donor oocytes – if required ( in case of vitrified oocytes provision).
    • Or donor stimulation and egg collection procedure – if required ( in case of fresh oocytes provision).
    • General anaesthetic for the donor – if required.
    • Patient egg collection procedure.
    • General anaesthetic for the patient.
    • The semen analysis and sperm preparation.
    • Intracytoplasmic sperm injection (ICSI) – if required.
    • Embryo culture of patient and donor embryos in separate culture dishes.
    • Egg donor compensation.
    • Embryo transfer.
    • Cryopreservation of embryos.
  • Embryo storage for one year.

Double Donation program

IVF program with egg and sperm donor – About the program

This package comprises an entire IVF treatments costs with both egg and sperm donors` gametes, ICSI fertilization, as well as cryopreservation and embryo storage for a whole year. Intended parents are provided with an extended Egg donor personal profile, detailed medical history and several photos (donor`s childhood and adulthood pictures)

IVF program with egg and sperm donor includes:

    • Initial consultation with fertility specialist (personal doctor and medical coordinator who will be in constant contact with you at all stages of your treatment).
    • 7-days free access to broad Egg and Sperm donor catalogs with completely screened donors with different phenotypes.
    • Free Egg donor selection process with personal assistance.
    • Personalized treatment plan.
    • Individual stimulation protocol for endometrium.
    • Egg donor medical and psychological screening, medication, stimulation.
    • Sperm donor medical and psychological screening.
    • Donor egg collection procedure with anesthesia.
    • Egg and sperm donors compensation.
    • The semen analysis and sperm preparation.
    • ICSI – Intracytoplasmic sperm injection.
    • Embryo culture.
    • Embryo transfer.
    • Cryopreservation of surplus embryos.
    • Embryo storage for one year.
    • Photo of transferred embryos.

Guaranteed Egg Donation Money Back Program

About the program

Guaranteed Egg Donation program offers multiple IVF cycles for a fixed price, significant savings and a 50% refund in case pregnancy is not achieved.

Money Back System

If no pregnancy is achieved (pregnancy is determined by the ultrasound examination which will confirm baby`s heartbeat on 6th week of pregnancy), 50% of the program total cost will be
refunded.

Guaranteed Egg Donation Money Back Program includes:

    • Initial consultation with fertility specialist (personal doctor and medical coordinator who will be in constant contact with you at all stages of treatment in person or online).
    • Personalised treatment planning for each patient.
    • Donor medical and psychological screening, medication, stimulation.
    • Endometrial preparation protocol.
    • Up to 3 donor egg collection procedures with anesthesia.
    • Egg donor compensation.
    • The semen analysis and sperm preparation.
    • Intracytoplasmic sperm injection (ICSI).
  • Embryo culture.
  • Cryopreservation of embryos.
  • Embryo storage for 16 months.
  • Assisted hatching.
  • Unlimited frozen embryo transfers
  • Sperm freezing and storage for 12 months.
  • Detailed embryological development report and photo of transferred embryos.

Embryo Adoption

About the program

The Embryo adoption program is a proven, successful process allowing families desiring to experience pregnancy and childbirth (single parents or married couples) to adopt remaining embryos from patients who have performed a successful IVF treatment at our clinic and donated surplus embryos to other future families. At our embryo storage we have more than 1000 cryopreserved embryos ready to be booked immediately. In 2016 we reached 60% clinical pregnancy rate with donated embryos with patients over 40 years old! In accordance with the newest research, the success rate of frozen embryo transfer cycles is nearly the same as fresh IVF cycles.

Advantages:

  • more than 1000 cryopreserved embryos;
  • 60% clinical pregnancy rate;
  • 35% Live birth rate.

Surrogacy Programs

Surrogacy By Country

When it comes to Surrogacy Programs, in coordination with our partner Art Egg Donation & Surrogacy and some Surrogacy Clinic in USA and Europe, we can offer a wide range of surrogacy programs in these countries:

  • California, USA
  • Ukraine
  • Canada
  • Georgia
  • Greece
  • Kenya
  • Thailand

We want to give the suitable information to all the kind of the Intended Parents and general idea of the following aspects:

  • Surrogacy Laws (of our available program countries)
  • Current workable programs
  • Parentage transfer and/or parents’ names on the birth certificate
  • LGBT options
  • Single parents’ options
  • Obtaining dual citizenship
  • Surrogacy costs

What is Link4MED?

Link4MED is a unique, patient-led service that manages every aspect of your IVF treatments abroad. From the moment you get in touch with us, we provide general advice, support and a host of other benefits designed to make your In vitro fertilization treatment and trip as affordable and comfortable as possible.

IVF Inquiry

Check what our IVF Clinics have to offer!

Contact us

Ask for your personal IVF Inquiry

If you would like to have more information or you have some questions, please contact us and we will get back with your Personal Treatment Plan in 48 hours!